Transporters in drug discovery and development : detailed concepts and best practice
Yurong Lai
Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments.
- A comprehensive overview of drug transporter families and their clinical relevance in drug discovery and development
- Balanced coverage of molecular biology aspects and functional outcomes
- State of art knowledge related to transporter-mediated DDI and the clinical relevance in pharmacokinetics, dynamics, and toxicity
درجه (قاطیغوری(:
کال:
2013
خپرونه:
1
خپرندویه اداره:
Woodhead Publishing Limited
ژبه:
english
صفحه:
748
ISBN 10:
190881828X
ISBN 13:
9781908818287
لړ (سلسله):
Woodhead Publishing series in biomedicine, number 50
فایل:
PDF, 8.36 MB
IPFS:
,
english, 2013